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The first
signs of type II diabetes are "highly prevalent" among
the growing number of children and adolescents with severe obesity,
according to Yale University researchers.
"This
study suggests that many obese children have a high risk for developing
type II diabetes," Health and Human Services Secretary Tommy
Thompson said in a statement. "Researchers have a lot of
information on how to prevent and treat type II diabetes in adults,
but we need to find better ways to prevent and treat the disease
in children."
The researchers
reported in the New England Journal of Medicine on their study
of 55 obese young children, aged 4 to 10, and 112 obese adolescents,
aged 11 to 18, all of whom were severely overweight.
One-quarter
of the young children, and one-fifth of the adolescents, showed
signs of impaired glucose tolerance, the result of resistance
to insulin, according to the researchers.
Four of the
older children also were found to to have previously undiagnosed
Type II diabetes, and three others with impaired glucose tolerance
ultimately developed diabetes during the four-year study.
In the younger
group, reduced glucose tolerance was much more common among the
girls than the boys.
"Impaired
glucose tolerance is highly prevalent among children and adolescents
with severe obesity, irrespective of ethnic group," the researchers
concluded.
Other sources: New England Journal of Medicine,
DHHS
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